Hydrolyzed Saccharomyces Lysate Extract

AKA: Yeast lysate, Saccharomyces cerevisiae lysate

Plant-Derived

Skin Conditioner

Ferment

Extract

Not Clean

Hydrolyzed Saccharomyces Lysate Extract is a cosmetic ingredient. Assessed as safe by the CIR.

CAS #

1204060-83-2

Form

Liquid

Functions

Skin Conditioning

A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.

Skin Protecting

Antioxidant

Anti-Inflammatory

Boosts Collagen

Shields skin from damage

Traditional Use

Yeast lysate technology emerged in the 1980s-1990s as a way to extract intracellular components from yeast for enhanced skin benefits. Originally developed to improve moisturization and skin resilience in anti-aging formulations.

EWG

CIR

Safe as used

Pregnancy

Yes

CIR Safety Findings

medical-approval

all-shades-safe

Phototoxicity Concern

Regulatory Status

USA✔ permitted

EU⚠ restricted

JAPAN⚠ restricted

CANADA⚠ restricted

Regulatory Agencies

EWG CIR FDA EU COSING Health Canada

Skin Types

●all-skin-types

Best For

Dullness

Pregnancy & Breastfeeding Safe

Yes

The paper trail

🔬Peer-reviewednone on file

⚖️Regulatory0 listings

🛡️Safety-assessed1 review →

Counts, not a verdict. A listing isn't a study. The trail, you decide.

Verified Jun 2026

Data: CosIng · EWG · CIR