Hydrolyzed Wheat Protein/PVP Crosspolymer

Hydrolyzed Wheat Protein/PVP Crosspolymer molecular structure
molecular structure · PubChem
Allergen Warning
⚠️ Gluten / Wheat
Synthetic
Occlusive
Skin Conditioner
Hair Care
Clean
Protein hydrolyzates, wheat, crosspolymer with 2-pyrrolidinone, 1-ethenyl-.
CAS #
222400-35-3
Form
Powder
State
Solid
Functions
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Hair Fixing
Creates Protective Barrier
Conditions Hair
Locks In Moisture
Anti-Aging Benefits
Antioxidant Protection
Creates protective layer
Softens and detangles hair
Holds hair in place
Traditional Use
A 20th-century synthetic creation combining hydrolyzed wheat protein with polyvinylpyrrolidone (PVP), developed to create improved film-forming and conditioning properties for haircare and skincare products.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
medical-approval
all-shades-safe
Potential Sensitizer
Concentration Guide
Industry max
Industry typically uses up to 1.0% in leave-on products (11 products reported). Source: CIR Safety Assessment (CIR Seq 624).
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR