Hydroxyacetophenone

Hydroxyacetophenone molecular structure
molecular structure · PubChem
AKA: 4'-Hydroxyacetophenone, 99-93-4, 1-(4-Hydroxyphenyl)ethanone, 4-Hydroxyacetophenone, P-HYDROXYACETOPHENONE, 4-Acetylphenol, P-Hydroxyphenyl methyl ketone, Ethanone, Methyl p-hydroxyphenyl ketone, Para-Hydroxyacetophenone
Synthetic
Antioxidant
Safety Concern
Clean
Ethanone, 1-(4-hydroxyphenyl)-,p-Hydroxyacetophenone
Solubility Practically insoluble or insoluble in water
Formula
C8H8O2
Mol. Weight
136.15
CAS #
99-93-4
Form
Powder
State
Dry Powder; Other Solid
Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Neutralizes Free Radicals
Traditional Use
Developed as a modern synthetic preservative and antioxidant in the late 20th century for use in cosmetic formulations, created to replace some natural preservatives with improved stability.
EWG
1
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR