OriginProduced from aromatic amine precursors and morpholine through synthetic organic chemistry methods. Synthesized via cyclization and oxidation reactions to create the morpholine ring structure.
3,4-Dihydro-2H-1,4-benzoxazin-6-ol
Formula
C8H9NO2
Mol. Weight
151.16
CAS #
26021-57-8
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Hair Dyeing
Colors Hair
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
5
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not a Sensitizer
1 study / 1 not sensitizing (CIR 130)
Not Phototoxic
Animal test found no phototoxicity in the CIR safety assessment (CIR 130)
Mixed Eye Irritation Results
1 study / 1 mixed / reactions slight (CIR 130)
Skin Irritant in Testing
1 study / 1 irritating / reactions slight (CIR 130)
Dermal Absorption 0.04–0.06%
4 results from in vitro tests in the CIR safety assessment (CIR 130)
murphy