AKA: Idebenone, 58186-27-9, 2-(10-hydroxydecyl)-5, 6-dimethoxy-3-methylcyclohexa-2, 5-diene-1, 4-dione, Idebenona, Raxone, Idebenonum, Sovrima, CV 2619
WHAT IS IT? Synthetic
Antioxidant
Clean
Origin Derived from ubiquinone (coenzyme Q10), a naturally occurring compound, modified with a long-chain alkyl ester. Synthesized through esterification of ubiquinone with decanol, creating a lipophilic derivative for enhanced skin penetration.
2,5-Cyclohexadiene-1,4-dione, 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-
IS IT FOR ME? Pregnancy & Breastfeeding Safe
Yes
WHAT’S IT DO? Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Neutralizes free radicals
CAN I TRUST THIS? The paper trail
🛡️ Safety-assessed 2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
IS IT CLEAN? CIR Safety Findings
Not a Sensitizer
1 study / 1 not sensitizing / plus 4 case reports (CIR 819)
Mixed Skin Irritation Results
1 study / 1 mixed (CIR 819)
Concentration Guide
CIR's newest survey reports no concentration of use.
CIR · 2018 survey
Regulatory Status
JAPAN ⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
murphy