murphyHydroxypalmitoyl Sphinganine
AKA: 190249-36-6, Mexanyl GAA, Hexadecanamide, HYDROXYPALMITOYL SPHINGANINE [INCI]
Synthetic
Skin Conditioner
Hair Care
Clean
1,3-Dihydroxy-2-amino-[(N-(2-hydroxy)-hexanedecanoyl]-octadecane
Formula
C34H69NO4
Mol. Weight
555.90
CAS #
190249-36-6
Form
Powder
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not an Eye Irritant
1 study / 1 not irritating (CIR 674)
Not a Skin Irritant
1 study / 1 not irritating (CIR 674)
Not a Sensitizer
1 study / 1 not sensitizing (CIR 674)
Concentration Guide
Leave-on0.0025–0.062%
Rinse-off0.0025–0.0049%
0%50%100%
CIR reported use · report published 2020
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR