Hydroxypropyl Methacrylate

AKA: Rocryl 410, 1, 2-Propanediol, Monomethacrylate, 2-methyl, Methacrylic acid, Monoester with 1, 2-propanediol, 2-Propenoic acid, 2-hydroxymethylethyl ester
Synthetic
Occlusive
Clean
OriginDerived from methacrylic acid and propylene oxide, belonging to the acrylic polymer chemical family. Synthesized through esterification of hydroxypropyl alcohol with methacrylic acid or its derivatives.
2-Propenoic acid, 2- methyl-, Monoester with 1,2-Propanediol
Solubility Limited solubility in water, sol in common organic solvents
Formula
C7H12O3
Mol. Weight
144.17
CAS #
27813-02-1
Form
Powder
State
Hydroxypropyl methacrylate appears as white liquid with a light unpleasant odor. May float or sink in water. (USCG, 1999)
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Creates Protective Barrier
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
2
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Skin Irritant in Testing
1 study / 1 irritating / reactions mild (CIR 339)
Mixed Sensitization Results
4 studies / 3 sensitizing / 1 not sensitizing / reactions weak / plus 9 case reports (CIR 339)
Concentration Guide
Leave-on0.8–23%
Rinse-offNot reported
0%50%100%
CIR reported use · 2020 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
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