Hydroxypropyl Methylcellulose Acetate/Succinate

Hydroxypropyl Methylcellulose Acetate/Succinate 1
molecular structure · PubChem CID 121950
AKA: Hypromellose acetate succinate, Hydroxypropylmethylcellulose acetate succinate, Hypromellose acetate succinate [NF], Hpmcas, Celluloseacetatesuccinate
Synthetic
Occlusive
Not Clean
OriginDerived from cellulose, a naturally occurring polymer found in plant cell walls, particularly wood pulp and cotton. Produced through chemical esterification and etherification of cellulose with acetic and succinic acid derivatives.
Cellulose, 2-hydroxypropyl methyl ether, acetate hydrogen butanedioate
Formula
C10H22O9
Mol. Weight
286.28
CAS #
71138-97-1
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Creates Protective Barrier
Reduces Inflammation
Locks In Moisture
Fights Bacteria
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed0 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR