murphyIsocetyl Myristate
AKA: ICM-R, Nikkol ICM-R, 83708-66-1, Myristic acid, Isocetyl ester, Tetradecanoic acid, Isohexadecyl ester
Synthetic
Emollient
Skin Conditioner
Clean
OriginSynthesized from myristic acid and isocetyl alcohol, both derived from petroleum or plant-based fatty acids. Produced through esterification, combining myristic acid with isocetyl alcohol under catalytic conditions.
Tetradecanoic acid, isohexadecy ester
Formula
C30H60O2
Mol. Weight
452.80
CAS #
83708-66-1
Form
Liquid
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
1 study / 1 not sensitizing (CIR 623)
Not a Skin Irritant
1 study / 1 not irritating (CIR 623)
Concentration Guide
Leave-on0.4–36.5%
Rinse-offNot reported
0%50%100%
CIR reported use · 2012 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR