Isocetyl Palmitate

AKA: Hexadecanoic acid, Isohexadecyl ester, TEGOSOFT HP, DERMOL ICP, ISOHEXADECYL PALMITATE, AEC ISOCETYL PALMITATE, PALMITIC ACID, ISOCETYL ESTER
Synthetic
Emollient
Skin Conditioner
Clean
OriginSynthesized from palmitic acid and isocetyl alcohol, both derived from petrochemical or plant oil sources. Produced through esterification, combining palmitic acid with isocetyl alcohol via catalytic reaction.
Hexadecanoic acid, isohexadecyl ester
Formula
C32H64O2
Mol. Weight
480.80
CAS #
127770-27-8
Form
Liquid
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
CIR's newest survey reports no concentration of use.
CIR · 2012 survey
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR