Isocetyl Palmitate

Isocetyl Palmitate molecular structure
molecular structure · PubChem
AKA: Hexadecanoic acid, Isohexadecyl ester, TEGOSOFT HP, DERMOL ICP, ISOHEXADECYL PALMITATE, AEC ISOCETYL PALMITATE, PALMITIC ACID, ISOCETYL ESTER
Synthetic
Emollient
Skin Conditioner
Clean
Hexadecanoic acid, isohexadecyl ester
Effective at 18.7%
Formula
C32H64O2
Mol. Weight
480.80
CAS #
127770-27-8
Form
Liquid
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
Traditional Use
Synthetic ester developed as a cosmetic emollient and skin-conditioning agent in the mid-20th century, designed to mimic natural oils while providing stable, predictable performance.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Concentration Guide
0.4%
37.0%
0%52%
Reported use
CIR reported use: 0.4-37
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR