Isodecyl Salicylate

AKA: 85252-25-1, Keratoplast, Benzoic acid, Isodecyl ester, EDESAL, DERMOL IDSA
Synthetic
Skin Conditioner
Chemical Exfoliant
Clean
The Panel concluded that the following ingredients are safe in cosmetics in the present practices of use and concentration described in the safety assessment, when formulated to be non-irritating and non-sensitizing, which may be based on a quantitative risk assessment (QRA)...Isodecyl Salicylate...
Formula
C17H26O3
Mol. Weight
278.40
CAS #
85252-25-1
Form
Liquid
Functions
Antistatic
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
Synthetic ester developed in the 20th century as a cosmetic emollient and preservative booster. Combines salicylic acid (historically used for acne and exfoliation) with isodecyl alcohol to create a stable, synthetic ingredient with no traditional use history.
EWG
1
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not an Irritant
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed3 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR