murphyIsodecyl Salicylate
AKA: 85252-25-1, Keratoplast, Benzoic acid, Isodecyl ester, EDESAL, DERMOL IDSA
Synthetic
Skin Conditioner
Clean
OriginDerived from salicylic acid and isodecyl alcohol, both synthetic organic compounds. Synthesized through esterification reaction between salicylic acid and isodecyl alcohol.
The Panel concluded that the following ingredients are safe in cosmetics in the present practices of use and concentration described in the safety assessment, when formulated to be non-irritating and non-sensitizing, which may be based on a quantitative risk assessment (QRA)...Isodecyl Salicylate...
Formula
C17H26O3
Mol. Weight
278.40
CAS #
85252-25-1
Form
Liquid
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Caution
Functions
Antistatic
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not an Eye Irritant
1 study / 1 not irritating (CIR 766)
Mixed Skin Irritation Results
2 studies / 1 mixed / 1 not irritating / reactions slight (CIR 302 and 766)
Concentration Guide
Leave-on2.5%
Rinse-offNot reported
0%50%100%
CIR reported use · 2018 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR