Isohexyl Neopentanoate

Isohexyl Neopentanoate molecular structure
molecular structure · PubChem
AKA: 2-Ethylbutyl 2, 2-dimethylpropanoate, 131141-70-3, Propanoic acid, 2-ethylbutyl ester, 2-Ethylbutyl pivalate
Synthetic
Emollient
Skin Conditioner
Not Clean
Propanoic acid, 2,2-dimethyl, 2-ethylbutyl ester
Formula
C11H22O2
Mol. Weight
186.29
CAS #
131141-70-3
Form
Oil
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
Traditional Use
Synthetic ester developed as a lightweight cosmetic emollient. Created in the 20th century to provide skin-conditioning properties without a traditional historical use.
EWG
3
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR