Isohexyl Palmitate

AKA: 59219-72-6, Isohexyl palmitate [INCI], Hexadecanoic acid, 4-methylpentyl ester, 4-METHYLPENTYL HEXADECANOATE
Synthetic
Emollient
Skin Conditioner
Not Clean
Hexadecanoic acid, 1-methylpentyl ester
Formula
C22H44O2
Mol. Weight
340.60
CAS #
55194-91-7
Form
Liquid
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
Traditional Use
Synthetic ester combining isohexyl alcohol with palmitic acid (found in palm oil). Developed as a modern cosmetic emollient designed to replicate natural fatty acid benefits in a standardized form.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed1 review
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR