Isoleucine

Isoleucine 1
molecular structure · PubChem CID 6306
AKA: L-isoleucine, 73-32-5, (2S, 3S)-2-Amino-3-methylpentanoic acid, 2S, 3S-Isoleucine, (S)-Isoleucine, (S, S)-Isoleucine, 2-Amino-3-methylvaleric acid, Erythro-L-Isoleucine, L-Ile
Synthetic
Skin Conditioner
Hair Care
Clean
OriginIsoleucine is a branched-chain amino acid from the aliphatic amino acid chemical family. It is synthesized through fermentation of glucose using genetically modified bacteria or chemical amino acid synthesis.
L-Isoleucine; DL-allo-Isoleucine; 2-Amino-3-methylpentanoic acid
Solubility 34400
Formula
C6H13NO2
Mol. Weight
131.17
CAS #
73-32-5, 443-79-8
Form
Powder
State
Waxy shiny solid; [Merck Index] White solid; [Sigma-Aldrich MSDS]
Skin Types
●all-skin-types
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
Functions
Antistatic
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
Leave-on0.0003–0.002%
Rinse-off0.001–0.002%
0%50%100%
CIR reported use · 2012 survey
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR