Isopentyldiol

AKA: 3-Methyl-1, 3-butanediol, 3-methylbutane-1, 3-diol, 2568-33-4, 1, 3-Butanediol, Isoprene glycol, ISOPENTYL DIOL, 3-hydroxy-3-methylbutanol, 3-methyl-1, 3-butandiol
Synthetic
Humectant
Solvent
Clean
OriginSynthesized from isoprene or isopentane, which are petrochemical-derived hydrocarbons from crude oil refining. Produced through chemical synthesis involving hydrogenation and alcohol formation reactions to create the diol compound.
Isopentyldiol is a cosmetic ingredient. Also known as 3-Methyl-1. Rated low hazard by EWG.
Formula
C5H12O2
Mol. Weight
104.15
CAS #
50468-22-9, 2568-33-4
Skin Types
●all-skin-types
Best For
General
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Provides scent
Dissolves other ingredients
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory0 listings
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Insufficient
Pregnancy
—
CIR Safety Findings
Not Phototoxic
Animal test found no phototoxicity in the CIR safety assessment (CIR 731)
Not a Sensitizer
1 study / 1 not sensitizing (CIR 731)
Not an Eye Irritant
1 study / 1 not irritating (CIR 731)
Mixed Skin Irritation Results
2 studies / 1 irritating / 1 mixed / reactions slight (CIR 731)
Regulatory Status
USAunder review
CANADA✔ permitted
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR