Isopropyl Cloprostenate

AKA: 157283-66-4, Cloprostenol isopropyl ester, Isopropyl cloprostenol, CPG-611295, 5-Heptenoic acid, 1-methylethyl ester
Synthetic
Skin Conditioner
Hair Care
Not Clean
Isopropyl Cloprostenate is a synthetic analogue of a prostaglandin.
Formula
C25H35ClO6
Mol. Weight
467.00
CAS #
157283-66-4
Form
Oil
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Anti-Inflammatory
Antioxidant
Improves Elasticity
Softens and detangles hair
Traditional Use
A synthetic analog of the prostaglandin cloprostenol developed for use in eyelash-growth cosmetics. Created to stimulate hair follicle activity and extend the anagen (growth) phase of eyelashes.
EWG
4
CIR
Reviewed by CIR
Pregnancy
No
CIR Safety Findings
all-shades-safe
Regulatory Status
USAunder review
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
Loss of Elasticity
Pregnancy & Breastfeeding Safe
No
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory1 listing
🛡️Safety-assessed1 review
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR