Isopropyl Hydroxystearate

AKA: Thatmat, Hydroxyoctadecanoic acid, 1-methylethyl ester, 74819-91-3, (+-)-ISOPROPYL HYDROXYSTEARATE, ISOPROPYL HYDROXYSTEARATE [INCI]
Plant-Derived
Emollient
Skin Conditioner
Not Clean
Octadecanoic acid, 12-hydroxy-, 1-methylethyl ester
Formula
C21H42O3
Mol. Weight
342.60
CAS #
74819-91-3
Form
Liquid
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
Traditional Use
Synthetic ester developed in the mid-20th century as a skin conditioning agent and emollient. Created to provide lightweight hydration and improve the texture of cosmetic formulations without the greasiness of natural oils.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed1 review
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR