Isopropyl Linoleate

AKA: Ceraphyl IPL, Isopropyl linolate, 22882-95-7, Linoleic acid, Isopropyl ester, 1-Methylethyl-9, 12-octadecadienoate, 1-methylethyl ester
Synthetic
Emollient
Skin Conditioner
Not Clean
OriginDerived from linoleic acid (an unsaturated fatty acid) and isopropyl alcohol, both petroleum or plant-based sources. Synthesized through esterification, combining linoleic acid with isopropanol using catalytic processes.
Isopropyl (9Z,12Z)-octadeca-9,12-dienoate
Formula
C21H38O2
Mol. Weight
322.50
CAS #
22882-95-7
Form
Liquid
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Binding
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
3
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Mixed Eye Irritation Results
4 studies / 2 irritating / 1 mixed / 1 not irritating / reactions slight (CIR 112 and 623)
Mixed Skin Irritation Results
7 studies / 4 irritating / 2 mixed / 1 not irritating / reactions slight (CIR 112 and 623)
Concentration Guide
Leave-on0.1%
Rinse-off0.1%
0%50%100%
CIR reported use · 2012 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
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