Isopropyl Myristate

AKA: 110-27-0, Isopropyl tetradecanoate, Isomyst, Tetradecanoic acid, 1-methylethyl ester, Bisomel, Estergel, Deltyl Extra, Propan-2-yl tetradecanoate, Kesscomir
Synthetic
Emollient
Fragrance
Skin Conditioner
Clean
OriginSynthesized from myristic acid (a saturated fatty acid) and isopropyl alcohol through esterification. Produced by combining myristic acid with isopropanol using acid catalysts to form the ester bond.
Tetradecanoic acid, isopropyl ester
Solubility Soluble in castor oil, cottonseed oil, acetone, chloroform, ethyl acetate, ethanol, toluene, and mineral oil; practically insoluble in glycerol, propylene glycol
Formula
C17H34O2
Mol. Weight
270.50
CAS #
110-27-0
Form
Liquid
State
Liquid
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Binding
Perfuming
Added for scent. Can be natural or synthetic. Common irritant and allergen — one of the top reasons people react to products.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not Phototoxic
Human test and Product formulation test found no phototoxicity in the CIR safety assessment (CIR 229 and 623)
Comedogenic in Testing
Animal test found comedogenicity in the CIR safety assessment (CIR 504 CIR 623)
Mixed Eye Irritation Results
3 studies / 2 irritating / 1 mixed / reactions minimal to mild (CIR 229 and 504 and 623)
Mixed Sensitization Results
10 studies / 1 mixed / 9 not sensitizing / plus 5 case reports (CIR 229 and 504 and 623)
Mixed Skin Irritation Results
24 studies / 16 irritating / 2 mixed / 6 not irritating / reactions minimal to severe (CIR 229 and 504 and 623)
Concentration Guide
Leave-on0.0002–77.3%
Rinse-off0.000005–67%
0%50%100%
CIR reported use · 2012 survey
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR