Isopropyl Thioglycolate
molecular structure · PubChem
AKA: 7383-61-1, Acetic acid, Isopropyl ester, 1-methylethyl ester, THIOGLYCOLIC ACID ISOPROPYL ESTER, ACETIC ACID, 1-METHYLETHYL ESTER
WHAT IS IT?
Synthetic
Not Clean
Acetic acid, mercapto-, 1-methylethyl ester
Formula
C5H10O2S
Mol. Weight
134.20
CAS #
7383-61-1
Form
Liquid
WHAT DOES IT DO?
Functions
Hair Waving Or Straightening
Anti-Inflammatory
Antioxidant
Improves Elasticity
Changes hair texture
Traditional Use
Developed in the mid-20th century as a chemical depilatory and hair-waving agent. Created to replace older, more caustic hair removal methods by offering safer controlled protein breakdown.
IS IT CLEAN?
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA
✔ permitted
EU
✔ permitted
JAPAN
✔ permitted
CANADA
✔ permitted
Regulatory Agencies
EWG
CIR
FDA
EU COSING
Health Canada
IS IT FOR ME?
Skin Types
●
all-skin-types
Best For
Rough Texture
Pregnancy & Breastfeeding Safe
Caution
CAN I TRUST THIS?
The paper trail
🔬
Peer-reviewed
none on file
⚖️
Regulatory
1 listing →
🛡️
Safety-assessed
1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR