Isopropylidenediphenyl Bisoxyhydroxypropyl Methacrylate

AKA: 1565-94-2, Nupol 1629, NuvaSeal, BISPHENOL A-GLYCIDYL METHACRYLATE, Epoxylite 9075, Enamel Bond, Concise, Bisphenol(a)glycidylmethacrylate, Concise Resins, Kerr Sealer
Synthetic
Occlusive
Not Clean
OriginDerived from phenol and methacrylic acid chemical families through synthetic organic chemistry. Synthesized via esterification and polymerization reactions to create the cross-linked film-forming polymer.
2-Propenoic Acid, 2-Methyl-, (1-Methylethylidene)Bis[4,1-Phenyleneoxy(2-Hydroxy-3,1-Propanediyl)]Ester
Formula
C29H36O8
Mol. Weight
512.60
CAS #
1565-94-2
Form
Powder
State
Liquid; [Aldrich MSDS]
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Creates Protective Barrier
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
5
CIR
Reviewed by CIR
Pregnancy
Caution
CIR Safety Findings
Sensitizer in Testing
1 study / 1 sensitizing / plus 7 case reports (CIR 339)
Concentration Guide
Leave-on4.3–9.5%
Rinse-offNot reported
0%50%100%
CIR reported use · 2020 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
murphy