Isopropylparaben

AKA: Isopropyl 4-hydroxybenzoate, 4191-73-5, Isopropyl p-hydroxybenzoate, P-Hydroxybenzoic acid isopropyl ester, Benzoic acid, 1-methylethyl ester, 1-Methylethyl-4-hydroxybenzoate, 4-Hydroxybenzoic acid
Synthetic
Preservative
Not Clean
OriginIsopropylparaben is synthesized from p-hydroxybenzoic acid, a compound in the paraben chemical family. It is produced through esterification of p-hydroxybenzoic acid with isopropyl alcohol.
The CIR Expert Panel concluded that the following 20 parabens are safe in cosmetics in the present practices of use and concentration described in the safety assessment when the sum of the combined concentration of parabens in any given formulation does not exceed 0.8 %...Isopropylparaben...
Formula
C10H12O3
Mol. Weight
180.20
CAS #
4191-73-5
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Preservative
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Preserves Formula
Reduces Inflammation
Fights Bacteria
UV Protection
Prevents microbial growth
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
10
CIR
Safe as used
Pregnancy
Yes
Restricted By
CIR Safety Findings
Skin Irritant in Testing
1 study / 1 irritating / reactions weak (CIR 746)
Sensitizer in Testing
1 study / 1 sensitizing (CIR 746)
Concentration Guide
Leave-on0.00004–0.32%
Rinse-off0.000005–0.22%
0%50%100%
CIR reported use · 2016 survey
Prohibited in EU cosmetics: EU Cosmetics Regulation (EC) 1223/2009, Annex II (Prohibited Substances), Entry 1374, added by Commission Regulation (EU) No 358/2014.
Regulatory Agencies
🧂Conflict of interest.
Verified Jun 2026 · 🧪 = conflict
Data: PubChem · CosIng · EWG · CIR
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