Isostearamidopropyl Betaine

AKA: Obazoline isab, Mackam isa, Schercotaine iab, 63566-37-0, Isostearamidopropyl betaine [INCI], 1-Propanaminium, N-(carboxymethyl)-N, Inner salt
Plant-Derived
Cleanser
Skin Conditioner
Hair Care
Not Clean
OriginDerived from coconut oil or palm kernel oil fatty acids and dimethylaminopropylamine. Synthesized through amidation of fatty acids followed by betaine quaternization.
1-Propanaminium, N-carboxymethyl-N,N-dimethyl-3-(1-oxoisooctadecylamino)-, hydroxide, inner salt
Formula
C25H50N2O3
Mol. Weight
426.70
CAS #
63566-37-0
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Antistatic
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Foam Boosting
Locks in moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed0 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Skin Irritant in Testing (CIR report on the ingredient group)
CIR report statement covering this group of ingredients / not tested individually (CIR 518)
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2012
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR