Isostearamidopropyl Dimethylamine

AKA: Isooctadecanamide, N-[3-(dimethylamino)propyl]isooctadecan-1-amide, MACKINE 401, N-(3-(Dimethylamino)propyl)isooctadecanamide, SCHERCODINE I AMIDO-AMINE, DIMETHYLAMINOPROPYLISOSTEARAMIDE
Plant-Derived
Not Clean
N-[3-(Dimethylamino)propyl]isooctadecan-1-amide
Formula
C23H48N2O
Mol. Weight
368.60
CAS #
67799-04-6
Form
Liquid
Functions
Antistatic
Reduces Static
Reduces Flyaways
Traditional Use
A synthetic quaternary ammonium compound developed in the mid-20th century for use as a conditioning and antistatic agent in hair and skincare products.
EWG
5
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory1 listing
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR