murphyIsostearyl Glyceryl Ether
AKA: Monoisostearyl glyceryl ether, GE-IS cpd, Penetol GE-IS, GE-IS, 78145-84-3, 1, 2-Propanediol
Plant-Derived
Skin Conditioner
Clean
OriginDerived from natural fatty alcohols and glycerin, typically sourced from vegetable oils like coconut or palm. Synthesized through etherification, chemically bonding glycerin with isostearyl alcohol under catalytic conditions.
3-Isooctadecyloxypropane-1,2-diol
Formula
C21H44O3
Mol. Weight
344.60
CAS #
78145-84-3
Form
Liquid
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not Phototoxic (CIR Panel on the ingredient group)
CIR Panel statement covering this group of ingredients; not tested individually (CIR 588)
Concentration Guide
Leave-on0.01–0.02%
Rinse-off0.001%
0%50%100%
CIR reported use · 2011 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR