Isostearyl Glyceryl Ether

Isostearyl Glyceryl Ether molecular structure
molecular structure · PubChem
AKA: Monoisostearyl glyceryl ether, GE-IS cpd, Penetol GE-IS, GE-IS, 78145-84-3, 1, 2-Propanediol
Plant-Derived
Skin Conditioner
Plant Oil
Clean
3-Isooctadecyloxypropane-1,2-diol
Formula
C21H44O3
Mol. Weight
344.60
CAS #
78145-84-3
Form
Liquid
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
A synthetic emollient derived from isostearyl alcohol and glycerin, developed in the late 20th century. Used in cosmetics to provide hydration, slip, and skin conditioning without excessive greasiness.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR