Isostearyl Linoleate

AKA: Protachem isl, 127358-80-9, Isostearyl linoleate [INCI], Isooctadecyl ester, 16-methylheptadecyl (9Z, 12Z)-octadeca-9, 12-dienoate
Plant-Derived
Emollient
Skin Conditioner
Clean
9,12-Octadecadienoic Acid (9Z,12Z)-, Isooctadecyl Ester
Formula
C36H68O2
Mol. Weight
532.90
CAS #
127358-80-9
Form
Liquid
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
Traditional Use
A synthetic ester combining isostearyl alcohol with linoleic acid, a naturally-occurring essential fatty acid. Developed to provide skin conditioning and barrier support benefits in modern skincare formulations.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed3 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR