Isostearyl Sebacate

AKA: Isostearyl sebacate [INCI], 478273-24-4
Plant-Derived
Skin Conditioner
Clean
Isostearyl Sebacate is the half-ester of isostearyl alcohol and sebacic acid. It conforms to the formula:
Formula
C28H54O4
Mol. Weight
454.70
CAS #
478273-24-4
Form
Liquid
Functions
Miscellaneous
Skin Conditioning Miscellaneous
Antioxidant Protection
Locks In Moisture
UV Protection
Improves skin feel
Traditional Use
A synthetic ester created as a cosmetic emollient and skin conditioning agent. Developed to provide hydration and improved texture in skincare formulations.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed1 review
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR