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Lactoglobulin
AKA “9045-23-2, Lactoglobulins, beta-, .beta.-, RefChem:798376, EINECS 232-928-9, 232-928-9, (2R, 4R)-2-methyl-4-[(4-octylphenyl)methoxy]pyrrolidine;hydrochloride, |A-Lactoglobulin, C20H34ClNO, 2-methyl-4-((4-octylbenzyl)oxy)pyrrolidine hydrochloride”
Skin Conditioning
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Ingredient Facts
Lactoglobulin
AKA: 9045-23-2, Lactoglobulins, Beta-, .beta.-, RefChem:798376, EINECS 232-928-9, 232-928-9, (2R, 4R)-2-methyl-4-[(4-octylphenyl)methoxy]pyrrolidine;hydrochloride, |A-Lactoglobulin, C20H34ClNO, 2-methyl-4-((4-octylbenzyl)oxy)pyrrolidine hydrochloride
Skin Conditioning · Antistatic · EWG: 1
Synthetic
Skin Conditioner
Hair Care
Amino Acid
Clean
Lactoglobulins, .beta.-
Formula
C20H34ClNO
Mol. Weight
339.90
CAS #
9045-23-2
Form
Powder
State
Powder; [Sigma-Aldrich MSDS]
See origin →
Functions
Antistatic
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
Lactoglobulin is a whey protein first identified in the late 19th century. Used in 20th-century cosmetics for its protein-conditioning and skin-barrier supporting properties.
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Beta-Carotene.
, 2006
→
Inhibitory effect of prostaglandin E1 on laurate-induced peripheral vascular occlusive sequelae in rabbits: optimized topical formulation with beta-cy
Adachi H, Irie T, Uekama K, Manako T, Yano T et al.
The Journal of pharmacy and pharmacology, 1992
→
Inhibitory effect of prostaglandin E1 on laurate-induced peripheral vascular occlusive sequelae in rabbits: optimized topical formulation with beta-cy
Adachi H, Irie T, Uekama K, Manako T, Yano T et al.
The Journal of pharmacy and pharmacology, 1992
→
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics.
Burnett CL, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
→
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics.
Burnett CL, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
→
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Beta-Alanine Diacetic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Beta-Caryophyllene
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Beta-Glucan Hydroxypropyltrimonium Chloride
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Beta-Glucan Palmitate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Beta-Sitosteryl Acetate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Hydrolyzed Beta-Glucan
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Lactoglobulin
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Oxidized Beta-Glucan
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Carboxymethyl Beta-Glucan
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
8'-Apo-Beta-Carotenal
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Beta-Caryophyllene
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Hydrolyzed Beta-Glucan
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Lactoglobulin
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sodium Carboxymethyl Beta-Glucan
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Mannitol Is a Good Anticaking Agent for Spray-Dried Hydroxypropyl-Beta-Cyclodextrin Microcapsules.
Kou X, Zhang X, Cheng Y, Yu M, Meng Q et al.
Molecules (Basel, Switzerland), 2023
→
Safety of alpha-arbutin and beta-arbutin in cosmetic products
Scientific Committee on Consumer Safety (SCCS)
European Commission — SCCS
→
Human beta-defensin-2.
Schröder JM, Harder J
The international journal of biochemistry & cell biology, 1999
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR