murphyLauramine Oxide
AKA: 1643-20-5, Lauryldimethylamine oxide, 1-Dodecanamine, N-oxide, LDAO, Dodecyldimethylamine oxide, Lauryldimethylamine N-oxide, Ammonyx AO, Ammonyx LO, Empigen OB
Synthetic
Cleanser
Fragrance
Skin Conditioner
Hair Care
Clean
OriginDerived from coconut or palm kernel oils, which contain lauric acid as a primary fatty acid component. Synthesized through oxidation of lauryl dimethylamine, a derivative created by aminating lauryl alcohol.
On the basis of the available animal and clinical data presented in this report, the CIR Expert Panel concludes that Lauramine Oxide and Stearamine Oxide are safe as cosmetic ingredients for "rinse-off" products under present conditions of use. For use in "leave-on" products, the Expert Panel concludes that Lauramine Oxide should be limited to 3.7% and Stearamine Oxide to 5%.
Solubility In water, 190,000 mg/L at 25 °C
Formula
C14H31NO
Mol. Weight
229.40
CAS #
1643-20-5
Form
Powder
State
Dimethyldodecylamine-n-oxide is a crystalline solid.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Antistatic
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Perfuming
Added for scent. Can be natural or synthetic. Common irritant and allergen — one of the top reasons people react to products.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Foam Boosting
Hydrotrope
Viscosity Controlling
Reduces Static
Removes Impurities
Conditions Hair
Adds Fragrance
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
3 studies / 3 not sensitizing (CIR 87)
Mixed Eye Irritation Results
2 studies / 1 irritating / 1 not irritating / reactions slight (CIR 87)
Mixed Skin Irritation Results
8 studies / 7 irritating / 1 not irritating / reactions slight to severe (CIR 87)
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR