Lauroyl Arginine

Lauroyl Arginine 1
molecular structure · PubChem CID 6451888
AKA: N-Lauroyl-L-arginine, N2-(1-Oxododecyl)-L-arginine, AMISAFE AL 01, AMISAFE AL-01
Synthetic
Skin Conditioner
Hair Care
Amino Acid
Clean
OriginDerived from the amino acid L-arginine and lauric acid, both synthetic or naturally-sourced compounds. Synthesized through amide bond formation between lauroyl chloride and arginine via condensation reaction.
The panel concluded that the 115 amino acid alkyl amides listed below are safe in the present practices of use and concentration in cosmetics, when formulated to be non-irritating...Lauroyl Arginine
Formula
C18H36N4O3
Mol. Weight
356.50
CAS #
42492-22-8
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not an Eye Irritant
1 study / 1 not irritating (CIR 645)
Concentration Guide
CIR's newest survey reports no concentration of use.
CIR · report published 2017
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR