Lauroyl Arginine

AKA: N-Lauroyl-L-arginine, N2-(1-Oxododecyl)-L-arginine, AMISAFE AL 01, AMISAFE AL-01
Synthetic
Skin Conditioner
Hair Care
Amino Acid
Clean
The panel concluded that the 115 amino acid alkyl amides listed below are safe in the present practices of use and concentration in cosmetics, when formulated to be non-irritating...Lauroyl Arginine
Formula
C18H36N4O3
Mol. Weight
356.50
CAS #
42492-22-8
Form
Powder
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
Synthetic derivative combining lauric acid with the amino acid arginine, developed in modern cosmetic chemistry to provide conditioning and antimicrobial properties in skincare and haircare products.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory1 listing
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR