Lauroyl Lysine

AKA: 52315-75-0, L-Lysine, N6-Lauroyl-L-lysine, Lauroyllysine, (2S)-2-amino-6-(dodecanoylamino)hexanoic acid, N6-(1-Oxododecyl)-L-lysine, ORISTAR LOL, AMIHOPE LL, FAMEX L 12
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Plant-Derived Synthetic
Skin Conditioner
Hair Care
Amino Acid
Clean
OriginNative to Synthetically produced, components can have diverse origins. Lauroyl lysine is derived from lysine, an amino acid commonly sourced from fermented plant proteins or synthetic production. It is synthesized by coupling lauric acid to lysine through an acylation reaction.
The panel concluded that the 115 amino acid alkyl amides listed below are safe in the present practices of use and concentration in cosmetics, when formulated to be non-irritating...Lauroyl Lysine...
Formula
C18H36N2O3
Mol. Weight
328.50
CAS #
52315-75-0
Form
Powder
Skin Types
●all-skin-types, gentle
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Viscosity Controlling
Locks in moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
2 studies / 2 not sensitizing (CIR 645)
Not a Skin Irritant
1 study / 1 not irritating (CIR 645)
Concentration Guide
Leave-on0.001–45%
Rinse-off0.001–0.3%
0%50%100%
CIR reported use · report published 2017
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR