Lysophosphatidylethanolamine

AKA: Monoacylglycerophosphoethanolamine, Lysophosphatidyl ethanolamine, ((2R)-3-acetyloxy-2-hydroxypropyl) 2-aminoethyl phosphate, [(2R)-3-acetyloxy-2-hydroxypropyl] 2-aminoethyl phosphate, Lyso-phosphatidyl ethanolamine, CHEBI:64574
Synthetic
Skin Conditioner
Not Clean
OriginDerived from phospholipid precursors and ethanolamine, belonging to the lysophospholipid chemical family. Synthesized through enzymatic or chemical hydrolysis of phosphatidylethanolamine to remove one fatty acid chain.
Lysophosphatidylethanolamine is the hydrolysate of phosphatidylethanolamine obtained by acid, enzyme or other method of hydrolysis
Formula
C7H15NO7P-
Mol. Weight
256.17
Form
Liquid
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2020
Regulatory Status
USA✔ permitted
EU✔ permitted
JAPAN✔ permitted
CANADA✔ permitted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR