Magnesium PCA
molecular structure · PubChem
AKA: Magnesium pyrrolidone carboxylate, Magnesium 2-oxopyrrolidine-5-carboxylate, 5819-47-6, Bis(5-oxo-DL-prolinato-N1, O2)magnesium, 85994-32-7, Magnesium L-pidolate
Synthetic
Humectant
Skin Conditioner
Clean
Magnesium 2-oxopyrrolidine-5-carboxylate
Formula
C10H12MgN2O6
Mol. Weight
280.52
CAS #
5819-47-6
Form
Powder
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks In Moisture
Traditional Use
A modern compound combining magnesium with pyrrolidone carboxylic acid, developed in the late 20th century. Created as a skin-conditioning agent to improve moisture retention in contemporary cosmetic formulations.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Concentration Guide
Dermal absorption: 5%. Source: CIR Safety Assessment (CIR Seq 683).
Regulatory Agencies
Skin Types
●all-skin-types
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
The New Tendency Complete Set
Nécessaire
calm & clarify duo
Cocokind
calming magnesium mist
Cocokind
travel-size Electrolyte Water Cream
Cocokind
hydration heroes set
Cocokind
The New Tendency Duo
Nécessaire
The Body Essentials
Nécessaire
The Body Lotion 70 ml | Multi-Peptide | Santal
Nécessaire
The Body Wash 100 ml | Multi-Mineral | Santal
Nécessaire
Dream Bio-Retinol Body Serum
OSEA
The Body Essentials Mini
Nécessaire
The Body Wash Discovery Collection
Nécessaire
travel-size calming magnesium mist
Cocokind
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR