Manganese Fructose Diphosphate

AKA: Manganese fructose-1, 6-bisphosphate, Fructose-1, 6-bisphosphate manganese salt
Synthetic
Antioxidant
Skin Conditioner
Not Clean
Manganese Fructose Diphosphate is the manganese salt of a complex mixture of esters of Fructose and phosphoric acid
CAS #
-
Form
Powder
Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Neutralizes free radicals
Traditional Use
A modern synthetic chelate compound created for cosmetic and nutritional applications in the late 20th century. Designed as a bioavailable form of manganese to deliver trace minerals to skin in contemporary skincare formulations.
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
medical-approval
all-shades-safe
Phototoxicity Concern
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
Dullness
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR