Methoxy PEG/PPG-25/4 Dimethicone

Methoxy PEG/PPG-25/4 Dimethicone molecular structure
molecular structure · PubChem
AKA: Silicone Surfactant
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Synthetic
Cleanser
Emulsifier
Silicone
Not Clean
OriginDerived from dimethicone, a siloxane polymer, combined with polyethylene glycol and polypropylene glycol. Synthesized through ethoxylation and propoxylation of dimethicone, followed by methyl ether formation.
Methoxy PEG/PPG-25/4 Dimethicone is the methyl ether of an alkyoxylated derivative of Dimethicone containing an average of 25 moles of ethylene oxide and 4 moles of propylene oxide
CAS #
-
Form
Liquid
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Emulsion Stabilising
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Stabilizes Emulsion
Emulsifier
Anti-Aging Benefits
Antioxidant Protection
Reduces Inflammation
Mixes oil and water
Keeps product blended
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
Leave-on0.8–1.1%
Rinse-offNot reported
0%50%100%
Reg. limit 30%
CIR reported use · report published 2014
FDA OTC limit: 30% (Skin Protectant). Source: FDA OTC Monograph, 21 CFR 347.10.
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: CosIng · EWG · CIR