Methoxydiglycol Methacrylate

AKA: 45103-58-0, 2-(2-Methoxyethoxy)ethyl methacrylate, MDM cpd, 2-Propenoic acid, 2-(2-methoxyethoxy)ethyl ester, BLEMMER PME 100, NK ESTER M 20G
Synthetic
Occlusive
Not Clean
OriginSynthesized from methoxydiglycol and methacrylic acid through esterification reactions in industrial chemical synthesis. The resulting ester is polymerized to form a film-forming polymer used in cosmetic formulations.
2-Propenoic acid, 2-Methyl-, 2-(2-Methoxyethoxy)Ethyl Ester
Formula
C9H16O4
Mol. Weight
188.22
CAS #
45103-58-0
Form
Liquid
State
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Creates Protective Barrier
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Caution
Concentration Guide
Leave-on24.8–65%
Rinse-offNot reported
0%50%100%
CIR reported use · 2020 survey
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR