Methoxyisopropanol

AKA: 1-Methoxy-2-propanol, 107-98-2, 1-Methoxypropan-2-ol, Closol, PGME, 2-Propanol, 1-Methoxy-2-hydroxypropane, Dowtherm 209, Propylene glycol monomethyl ether
Synthetic
Fragrance
Solvent
Not Clean
OriginSynthesized from propylene glycol and methyl ethers within the alcohol compound family. Produced through etherification reactions combining propylene glycol with methanol under catalytic conditions.
1-methoxypropan-2-ol; propyleneglycol monomethylether
Solubility greater than or equal to 100 mg/mL at 66 °F (NTP, 1992)
Formula
C4H10O2
Mol. Weight
90.12
CAS #
107-98-2
Form
Liquid
State
1-methoxy-2-propanol appears as a colorless liquid. Flash point near 89 °F. Less dense than water. Contact irritates skin, eyes and mucous membranes. Prolonged exposure to vapors may cause coughing, s
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Perfuming
Added for scent. Can be natural or synthetic. Common irritant and allergen — one of the top reasons people react to products.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Adds Fragrance
Dissolves Ingredients
Adds pleasant scent
Dissolves other ingredients
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Caution
Restricted By
CIR Safety Findings
Not a Sensitizer
1 study / 1 not sensitizing (CIR 355)
Mixed Skin Irritation Results
3 studies / 1 irritating / 2 mixed / reactions slight to mild (CIR 355)
Mixed Eye Irritation Results
4 studies / 3 irritating / 1 mixed / reactions slight to moderate (CIR 355)
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
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