Methoxyisopropyl Acetate

AKA: Propylene glycol methyl ether acetate, PGMEA cpd, 1-Methoxy-2-propyl acetate, 108-65-6, 1-methoxypropan-2-yl acetate, Propylene glycol monomethyl ether acetate, 2-Acetoxy-1-methoxypropane, 1-Methoxy-2-acetoxypropane
Synthetic
Solvent
Not Clean
2-methoxy-1-methylethyl acetate
Solubility In water, 1.98X10+5 mg/L at 25 °C
Formula
C6H12O3
Mol. Weight
132.16
CAS #
108-65-6
Form
Liquid
State
Propylene glycol methyl ether acetate is a colorless liquid with a sweet ether-like odor. (USCG, 1999)
Functions
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Dissolves Ingredients
Dissolves other ingredients
Traditional Use
A modern synthetic solvent created for cosmetic formulations. Used in skincare and color cosmetics to improve texture, evaporation, and product performance.
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR