Methyl Cyclodextrin

Synthetic
Chelating Agent
Clean
OriginDerived from cyclodextrin, a cyclic oligosaccharide typically produced from starch sources like corn or potatoes. Synthesized by methylation of cyclodextrin molecules using methyl iodide or dimethyl sulfate as methylating agents.
See also: beta-Cyclodextrin, methyl ethers (annotation moved to); Methyl Cyclodextrin (annotation moved to).
Formula
C37H62O30
Mol. Weight
986.90
CAS #
128446-36-6
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Chelating
Grabs onto metal ions in water that would destabilize the formula. Keeps your product from going bad or changing color.
Removes Metal Ions
Anti-Aging Benefits
Antioxidant Protection
Reduces Inflammation
Binds metal ions
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
Leave-on4–5%
Rinse-offNot reported
0%50%100%
CIR reported use · 2013 survey
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR