Methyl Glucose Sesquistearate

AKA: METHYL GLUCOSE SESQUISTEARATE (II), METHYL GLUCOSE SESQUISTEARATE [II], GRILLOCOSE PS, GLUCATE SS, TEGO CARE PS, METHYL GLUCOSE SESQUISTEARATE [INCI], METHYL GLUCOSIDE SESQUIPALMITOSTEARATE, D-GLUCOPYRANOSIDE, PALMITOSTEARATE (2:3)
Plant-Derived
Emollient
Cleanser
Emulsifier
Skin Conditioner
Clean
OriginDerived from glucose and stearic acid, typically sourced from plant oils like coconut or palm. Created through esterification of glucose with stearic acid via chemical synthesis.
D-Glucopyranoside, methyl, octadecanoate (2:3)
Formula
C68H133O18-3
Mol. Weight
1238.80
CAS #
68936-95-8
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not an Eye Irritant
1 study / 1 not irritating (CIR 617)
Not a Sensitizer
2 studies / 2 not sensitizing / plus 2 case reports (CIR 617)
Mixed Skin Irritation Results
3 studies / 1 irritating / 2 not irritating / reactions mild (CIR 617)
Concentration Guide
Leave-on0.3–5.19%
Rinse-off0.4–4%
0%50%100%
CIR reported use · 2013 survey
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR