AKA: 104191-95-9, GAMME, Glycyrrhizic acid methyl ester, (2S, 3S, 4S, 5R, 6R)-6-[(2S, 3R, 5S, 6S)-2-[[(3S, 4aR, 6aR, 6bS, 8aS, 11S, 12aR, 14aR, 14bS)-11-methoxycarbonyl-4, 4, 6a, 6b, 8a, 11, 14b-heptamethyl-14-oxo-2, 3, 4a, 5, 6, 7, 8, 9, 10, 12, 12a, 14a-dodecahydro-1H-picen-3-yl]oxy]-6-carboxylato-4, 5-dihydroxyoxan-3-yl]oxy-3, 5-trihydroxyoxane-2-carboxylate
WHAT IS IT? Synthetic
Fragrance
Not Clean
Origin Derived from glycyrrhizin, the main active compound extracted from licorice root (Glycyrrhiza glabra). Produced through esterification of glycyrrhizin with methanol to create the methyl ester derivative.
alpha-d-Glucopyranosiduronic acid, (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-o-beta-d-glucopyranuronosyl-, methyl ester; Glycyrrhizic acid methyl ester
IS IT FOR ME? Pregnancy & Breastfeeding Safe
Yes
CAN I TRUST THIS? The paper trail
🔬 Peer-reviewed none on file
🛡️ Safety-assessed 2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
IS IT CLEAN? CIR Safety Findings
Not Phototoxic (CIR Panel on the ingredient group)
CIR Panel statement covering this group of ingredients; not tested individually (CIR 349)
Regulatory Status
JAPAN ⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
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