Morpholine
molecular structure · PubChem
AKA: 110-91-8, 1-Oxa-4-azacyclohexane, Diethylene oximide, Tetrahydro-1, 4-oxazine, Diethylenimide oxide, Diethyleneimide oxide, Diethylene imidoxide, Drewamine, Tetrahydro-2H-1
Synthetic
Not Clean
Morpholine is an organic heteromonocyclic compound whose six-membered ring contains four carbon atoms and one nitrogen atom and one oxygen atom that lies opposite to each other; the parent compound of the morpholine family. It is a saturated organic heteromonocyclic parent and a member of morpholines. It is a conjugate base of a morpholinium.
Solubility Soluble (NTP, 1992)
Formula
C4H9NO
Mol. Weight
87.12
CAS #
110-91-8
Form
Liquid
State
Morpholine appears as a colorless liquid with a fishlike odor. Flash point 100 °F. Corrosive to tissue. Less dense than water and soluble in water. Vapors heavier than air. Used to make other chemical
Functions
Buffering
Anti-Inflammatory
Antimicrobial
Fights Acne
Maintains optimal pH
Traditional Use
Developed in the early 20th century as an organic compound in industrial chemistry. Adopted in cosmetics as a pH adjuster and buffering agent, particularly in formulations requiring stable acidity control.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory0 listings
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026 · 🧪 = conflict
Data: PubChem · CosIng · EWG · CIR