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Myristyl Betaine
AKA “2601-33-4, 1-Tetradecanaminium, N-(carboxymethyl)-N, N-dimethyl-, inner salt, Myristyl dimethyl glycine, Myristyl dimethyl betaine, (Carboxylatomethyl)dimethyltetradecylammonium, 95C19D1X0B, EINECS 220-006-9, N-TETRADECYL BETAINE, hydroxide”
Surfactant
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Ingredient Facts
Myristyl betaine
AKA: 2601-33-4, 1-Tetradecanaminium, N-(carboxymethyl)-N, N-dimethyl-, Inner salt, Myristyl dimethyl glycine, Myristyl dimethyl betaine, (Carboxylatomethyl)dimethyltetradecylammonium, 95C19D1X0B, EINECS 220-006-9, N-TETRADECYL BETAINE, Hydroxide
Surfactant · Cleansing · EWG: 1
Synthetic
Cleanser
Skin Conditioner
Hair Care
Amino Acid
Plant Oil
Clean
(Carboxylatomethyl)dimethyltetradecylammonium
Effective at 4.91%
Formula
C18H37NO2
Mol. Weight
299.50
CAS #
2601-33-4
Form
Liquid
State
Liquid
See origin →
Functions
Antistatic
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Foam Boosting
Locks in moisture
Traditional Use
Developed in the mid-20th century as a synthetic amphoteric surfactant derived from myristic acid (a fatty acid from coconut and palm oils). Created to provide mild cleansing properties while reducing skin irritation compared to harsher detergents.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Concentration Guide
0.015%
9.8%
0%14%
Effective Range
CIR reported use: 0.53-9.8 | 0.015-8.8
Regulatory Status
USA✔ permitted
CANADA✔ permitted
Regulatory Agencies
Final Report: Safety Assessment of Ammonia and Ammonium Hydroxide as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Safety Assessment of Alumina and Aluminum Hydroxide as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Safety Assessment of Inorganic Hydroxides as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Ammonium Hydroxide
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Calcium Hydroxide
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Iron Hydroxide
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Hydroxide
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Myristyl Betaine
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Potassium Hydroxide
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Zinc Ascorbate Hydroxide
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Zinc Carbonate Hydroxide
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Aluminum Hydroxide
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Ammonium Hydroxide
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Calcium Hydroxide
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Iron Hydroxide
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Hydroxide
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Myristyl Betaine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Potassium Hydroxide
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sodium Hydroxide
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Zinc Carbonate Hydroxide
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Properties and applications of calcium hydroxide in endodontics and dental traumatology.
Mohammadi Z, Dummer PM
International endodontic journal, 2011
→
Impact of Dietary Zinc Chloride Hydroxide and Zinc Methionine on the Faecal Microbiota of Healthy Adult Horses and Ponies.
Paßlack N, van Bömmel-Wegmann S, Vahjen W, Zentek J
Journal of equine veterinary science, 2022
→
Development of magnesium hydroxide-doped nanofibrous spheres for repairing infected skin wounds.
You Y, Ning X, Zhang X, Wang Y, Zhang Y et al.
Biomaterials advances, 2024
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR