N-Phenyl-p-Phenylenediamine

AKA: 4-Aminodiphenylamine, 101-54-2, P-AMINODIPHENYLAMINE, P-Anilinoaniline, Variamine Blue RT, Azosalt R, Luxan Black R, P-Semidine, N-Phenyl-1, 4-phenylenediamine
Synthetic
Not Clean
OriginSynthesized from aniline and para-phenylenediamine through aromatic amine chemistry and coupling reactions. Produced via controlled oxidative coupling or condensation synthesis under industrial chemical conditions.
N-(4-Aminophenyl)aniline (CI 76085)
Solubility less than 1 mg/mL at 66 °F (NTP, 1992)
Formula
C12H12N2
Mol. Weight
184.24
CAS #
101-54-2
Form
Liquid
State
N-phenyl-p-phenylenediamine appears as odorless purple-black solid or flake or dark purple chips. (NTP, 1992)
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
No
Allergen Warning
⚠️ PPD (Hair Dye)
Functions
Hair Dyeing
Boosts Collagen
Fights Acne
Colors hair
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
10
CIR
Safe as used
Pregnancy
No
CIR Safety Findings
Eye Irritant in Testing
1 study / 1 irritating (CIR 81)
Mixed Skin Irritation Results
3 studies / 1 irritating / 1 mixed / 1 not irritating (CIR 81)
Sensitizer in Testing
2 studies / 2 sensitizing / plus 6 case reports (CIR 81)
Regulatory Status
USA✔ permitted
EU✔ permitted
JAPAN✔ permitted
CANADA✔ permitted
🧂Conflict of interest.
Verified Jun 2026 · 🧪 = conflict
Data: PubChem · CosIng · EWG · CIR