Neopentyl Glycol Diethylhexanoate

AKA: 28510-23-8, NEOPENTYL GLYCOL DIOCTANOATE, Neopentyl glycol di(2-ethylhexoate), Neopentyl glycol di(2-ethylhexanoate), Neopentyl glycol bis(2-ethylhexanoate), SCHERCEMOL NGDO, KAK-NDO
Synthetic
Emollient
Skin Conditioner
Clean
2,2-Dimethyl-1,3-propanediyl diethylhexanoate
Formula
C21H40O4
Mol. Weight
356.50
CAS #
28510-23-8
Form
Liquid
State
Liquid
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
Traditional Use
A synthetic ester created for the cosmetics industry as a conditioning and emollient agent, designed to provide a silky texture and improve product feel on skin.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
CANADApermitted
Regulatory Agencies
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory1 listing
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR