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Neopentyl Glycol Diheptanoate
AKA “2, 2-Dimethylpropane-1, 3-diyl bisheptanoate, EINECS 248-687-8, 5LKW3C543X, Heptanoic acid, 1, 1'-(2, 2-dimethyl-1, 3-propanediyl) ester, 3-propanediyl ester, HEPTANOIC ACID 2, 2-DIMETHYLTRIMETHYLENE ESTER, 3-PROPANEDIOL, 2-DIMETHYL-, DIHEPTANOATE, HEPTANOIC ACID, 2-DIMETHYL-1, 3-PROPANEDIYL DIESTER, RefChem:832330”
Emollient
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Ingredient Facts
Neopentyl glycol diheptanoate
AKA: 2, 2-Dimethylpropane-1, 3-diyl bisheptanoate, EINECS 248-687-8, 5LKW3C543X, Heptanoic acid, 1, 1'-(2, 2-dimethyl-1, 3-propanediyl) ester, 3-propanediyl ester, HEPTANOIC ACID 2, 2-DIMETHYLTRIMETHYLENE ESTER, 3-PROPANEDIOL, 2-DIMETHYL-, HEPTANOIC ACID, 2-DIMETHYL-1, 3-PROPANEDIYL DIESTER, RefChem:832330
Emollient · Emollient · EWG: 1
Synthetic
Emollient
Skin Conditioner
Clean
2,2-Dimethyl-1,3-propanediyl diheptanoate
Formula
C19H36O4
Mol. Weight
328.50
CAS #
27841-04-9, 85711-80-4, 68855-18-5
Form
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
Traditional Use
A modern synthetic ester developed for cosmetic use to enhance product texture and provide light emollient properties in skincare and color cosmetic formulations.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
CANADA✔ permitted
Regulatory Agencies
Neopentyl Glycol Diheptanoate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-4 Diheptanoate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Neopentyl Glycol Diheptanoate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-4 Diheptanoate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Progress in 1,3-propanediol biosynthesis.
Li B, Gao W, Pan Y, Yao Y, Liu G
Frontiers in bioengineering and biotechnology, 2024
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Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function.
Pinto JR, Monteiro E Silva SA, Leonardi GR
International journal of cosmetic science, 2024
→
Fragrance material review on 2,2-dimethyl-3-phenylpropanol.
Scognamiglio J, Jones L, Letizia CS, Api AM
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2012
→
Reaction strategies for the enzymatic synthesis of neopentyl glycol diheptanoate.
Serrano-Arnaldos M, García-Martínez JJ, Ortega-Requena S, Bastida J, Máximo F et al.
Enzyme and microbial technology, 2020
→
Reaction strategies for the enzymatic synthesis of neopentyl glycol diheptanoate.
Serrano-Arnaldos M, García-Martínez JJ, Ortega-Requena S, Bastida J, Máximo F et al.
Enzyme and microbial technology, 2020
→
Reaction strategies for the enzymatic synthesis of neopentyl glycol diheptanoate.
Serrano-Arnaldos M, García-Martínez JJ, Ortega-Requena S, Bastida J, Máximo F et al.
Enzyme and microbial technology, 2020
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR