N,N-Bis(2-Hydroxyethyl)-p-Phenylenediamine Sulfate

AKA: 54381-16-7, N-Bis(2-hydroxyethyl)-p-phenylenediamine sulphate, Ethanol, Sulfate (1:1) (salt), COLOREX NNBIS, JAROCOL BHP, (p-Ammoniophenyl)bis(2-hydroxyethyl)ammonium sulphate, Sulfate (salt)
Allergen Warning
⚠️ PPD (Hair Dye)
Synthetic
Safety Concern
Not Clean
(p-Ammoniophenyl)bis(2-hydroxyethyl)ammonium sulphate
Formula
C10H18N2O6S
Mol. Weight
294.33
CAS #
54381-16-7
Form
Powder
Functions
Hair Dyeing
Wound Healing
Moisturizing
Strengthens Barrier
Colors hair
Traditional Use
A synthetic chemical dye intermediate developed in the 20th century for hair coloring applications. Part of the modern chemical oxidative hair dye system that replaced plant-based hair colorants.
EWG
6
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUpermitted
JAPANpermitted
CANADApermitted
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory1 listing
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR