N,N-Bis(Hydroxyethyl)-p-Phenylenediamine Sulfate

AKA: Hydroxyethyl -p-Phenylenediamine Sulfate
Synthetic
Cleanser
Not Clean
OriginSynthesized from p-phenylenediamine, a coal tar-derived aromatic amine compound used in organic synthesis. Produced through sulfonation and hydroxyethylation reactions to create the final hair dye intermediate.
N,N-Bis(Hydroxyethyl)-p-Phenylenediamine Sulfate is a cosmetic ingredient. Assessed as safe by the CIR.
Formula
C10H18N2O6S
Mol. Weight
294.33
CAS #
54381-16-7
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Allergen Warning
⚠️ PPD (Hair Dye)
Functions
Surfactant
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Hair Dyeing
Moisturizing
Wound Healing
Improves Elasticity
Colors hair
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory0 listings
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not Phototoxic
Animal test found no phototoxicity in the CIR safety assessment (CIR 115)
Sensitizer in Testing
3 studies / 3 sensitizing (CIR 115)
Regulatory Status
USA✔ permitted
CANADA✔ permitted
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR