Nonoxynol-10

AKA: 4-Methoxypicolinamide, 90151-10-3, 4-methoxypyridine-2-carboxamide, 4-Methoxy-pyridine-2-carboxylic acid amide, 9014-93-1, 4-Methoxypyridine-2-carboxylic acid amide, 2-Pyridinecarboxamide
Synthetic
Cleanser
Not Clean
OriginDerived from polyethylene glycol and nonylphenol, both petroleum-derived synthetic compounds. Synthesized through ethoxylation, where ethylene oxide is added to nonylphenol under catalytic conditions.
Poly(oxy-1,2-ethanediyl), .alpha.-(dinonylphenyl)-.omega.-hydroxy- (10 mol EO average molar ratio)
Formula
C7H8N2O2
Mol. Weight
152.15
CAS #
9014-93-1
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Cleansing Surfactant
Fights Bacteria
Removes Impurities
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory0 listings
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
3
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Mixed Phototoxicity Results
Both phototoxic and non-phototoxic results in the CIR safety assessment (CIR 695)
Eye Irritant in Testing
2 studies / 2 irritating / reactions slight to severe (CIR 212)
Mixed Skin Irritation Results
4 studies / 3 irritating / 1 mixed / reactions slight to moderate (CIR 212 and 695)
Concentration Guide
CIR's newest survey reports no concentration of use.
CIR · 2014 survey
Regulatory Status
USA✔ permitted
CANADA✔ permitted
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR