Nonoxynol-35
molecular structure · PubChem
AKA: Nonoxynol 35, POE(35) nonylphenol, Nonylphenol ethoxylate 35
Synthetic
Skin Conditioner
Not Clean
Nonoxynol-35 is a cosmetic ingredient. Assessed as safe by the CIR.
Form
Liquid
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Traditional Use
Developed in the mid-20th century as a nonionic surfactant and emulsifier. Used in cosmetics and personal care products for its ability to solubilize oils and improve product texture, with no traditional or historical use prior to synthetic polymer development.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory0 listings
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR