Nonoxynol-35

Nonoxynol-35 molecular structure
molecular structure · PubChem
AKA: Nonoxynol 35, POE(35) nonylphenol, Nonylphenol ethoxylate 35
Synthetic
Skin Conditioner
Not Clean
OriginDerived from ethylene oxide and nonylphenol, members of the synthetic surfactant chemical family. Synthesized through ethoxylation, where ethylene oxide chains are added to nonylphenol molecules.
Nonoxynol-35 is a cosmetic ingredient. Assessed as safe by the CIR.
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory0 listings
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Caution
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2015
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: CosIng · EWG · CIR